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Hacking the 3 Pathways of Aging

Mic the Vegan

Harvard biologist and researcher David Sinclair has made some incredible claims about longevity with a focus on pills but is there more to lifestyle and diet that we can hack than he usually discusses?

This video has 36 studies cited. – Links and Sources – Support Me Here: https://www.patreon.com/micthevegan My Cookbook: https://micthevegan.com/product/mics-…https://www.facebook.com/mictheveganhttps://www.instagram.com/micthevegan – @micthevegan TIY Tiny House Channel: https://www.youtube.com/channel/UCYht… My New Newsletter Sign-Up: https://mailchi.mp/2785ad113ff7/micth… Rich Roll Interview: https://www.youtube.com/watch?v=DGC-C… BROAD Study: https://www.nature.com/articles/nutd2… AMPK Study with Figure 2: https://www.nature.com/articles/emm20… AMPK Nexus of Aging Paper:  https://www.ncbi.nlm.nih.gov/pmc/arti… AMPK Metabolism Paper (Mitochondria): https://www.sciencedaily.com/releases… AMPK Aging Sensor Paper (Restriction Activates): https://www.ncbi.nlm.nih.gov/pmc/arti… Excess Calories and AMPK: https://www.nature.com/articles/emm20… Metformin and AMPK: https://www.frontiersin.org/articles/… Met Lowers Diabetes Mortality (50%): https://care.diabetesjournals.org/con… Met Lowers Diabetes Mortality (28%): https://pubmed.ncbi.nlm.nih.gov/28802… Met Extends Diabetic’s Life 15% Longer Than Control: https://dom-pubs.onlinelibrary.wiley…. AMPK and Exercise Main: https://pubmed.ncbi.nlm.nih.gov/19196… AMPK and HIIT: https://pubmed.ncbi.nlm.nih.gov/19112… AMPK Disappointing Fasting Result in Obese People: https://journals.physiology.org/doi/f… Muscle Mass and Longevity: https://www.ncbi.nlm.nih.gov/pmc/arti… Okinawan Paper: https://pubmed.ncbi.nlm.nih.gov/17986… Autophagy Paper: https://www.frontiersin.org/articles/… mTOR Paper Main: https://www.frontiersin.org/articles/… IGF-1 Vegans: https://pubmed.ncbi.nlm.nih.gov/12433… Dairy and IGF-1: https://pubmed.ncbi.nlm.nih.gov/20046… Rapamycin Increased Mouse Longevity: https://www.ncbi.nlm.nih.gov/pmc/arti… Curcumin Golden TORGET:  https://www.ncbi.nlm.nih.gov/pmc/arti… Source of Dietary mTOR Inhibitors: https://www.ncbi.nlm.nih.gov/pmc/arti… ECGC Tea: https://www.ncbi.nlm.nih.gov/pmc/arti… Sirtuin Paper: https://www.ahajournals.org/doi/10.11… Sirtuin Anor-xia: https://www.frontiersin.org/articles/… Anor-xia Mortality: https://jamanetwork.com/journals/jama… Resveratrol Lowers IGF-1: https://pubmed.ncbi.nlm.nih.gov/20935… Neurovascular coupling/brain blood flow in diabetics:  https://www.ncbi.nlm.nih.gov/pmc/arti… Increases T Killer Cells, decrease in inflammatory cytokines: https://pubmed.ncbi.nlm.nih.gov/28546… NAD and Sirtuins Takes 2 to Tango: https://www.nature.com/articles/npjam… NMN Mouse Study: https://www.sciencedirect.com/science… NMN is the fountain of youth…if you are a mouse: https://khn.org/news/a-fountain-of-yo… NR Raised NAD: https://academic.oup.com/ajcn/article… NMN Safe in 10 People: https://www.jstage.jst.go.jp/article/… Foods with NMN: https://www.sciencedaily.com/releases… Antioxidant Diet = 38% lower all-cause mortality:  https://link.springer.com/article/10…. Pilots DNA Damage and Antioxidants from Diet: https://pubmed.ncbi.nlm.nih.gov/19793… Intro/Outro Song: Sedução Momentânea by Roulet: http://freemusicarchive.org/music/Rou…#DavidSinclair#Aging#Longevity

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