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NAD+

Why NAD declines with age and what may prevent it


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https://www.youtube.com/channel/UC_vI… NAD-levels decline with age and now scientists have found out the mechanism behind it. We know that it is due to higher levels of the enzyme CD38. We also know that there are CD38-inhibitors, even natural ones like quercetin. The question is if we can use natural inhibitors, like quercetin, to stop the age related NAD decline. In mice this seems to be possible with artificial inhibitors.

A R T I C L E Read my article on “Information theory of Ageing”: http://stayonthehealthtrack.com/infor…

P A T R E O N Sponsor me on Patreon so that I can make lots more… http://patreon.com/basia Even a tiny amount will make a difference for me. R E F E R E N C E S The two papers I referenced to in the video are: “CD38 dictates age-related NAD decline and mitochondrial dysfunction through a SIRT3-dependent mechanism” https://www.ncbi.nlm.nih.gov/pmc/arti… “A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline” https://www.cell.com/cell-metabolism/…

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